[HTML][HTML] Amylin-induced downregulation of hippocampal neurogenesis is attenuated by leptin in a STAT3/AMPK/ERK-dependent manner in mice
HS Moon, F Dincer, CS Mantzoros - Diabetologia, 2013 - Springer
Aims/hypothesis Both leptin and insulin sensitivity have been linked with pathophysiological
processes involving the central nervous system in general, and the hippocampus in
particular, but the role of leptin in hippocampal neurogenesis has not yet been elucidated.
Also, no previous studies have evaluated whether amylin or the endogenous insulin
sensitiser adiponectin interact with leptin to alter hippocampal neurogenesis in mouse
hippocampal neuronal (HN) cells or investigated the role of leptin, amylin or adiponectin …
processes involving the central nervous system in general, and the hippocampus in
particular, but the role of leptin in hippocampal neurogenesis has not yet been elucidated.
Also, no previous studies have evaluated whether amylin or the endogenous insulin
sensitiser adiponectin interact with leptin to alter hippocampal neurogenesis in mouse
hippocampal neuronal (HN) cells or investigated the role of leptin, amylin or adiponectin …
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